マイクロRNAによる骨格筋量の調節

Skeletal muscle is a vital tissue not only for maintaining posture and body movements but also energy metabolism in human body. highly plastic response to various stimuli, resistance exercise or anabolic hormones can increase mass, which termed “muscle hypertrophy”. Contrary, immobility, aging severe illness reduce atrophy”. Loss of skeletal mass associated with loss independent living, the morbidity variety diseases mortality throughout life. Therefore, understanding mechanisms that regulate essential improving quality Recent studies reported microRNAs (miRNAs), class non-coding RNAs, play crucial role regulation mass. This review provides current function miRNAs